About

I am a Senior Data Scientist at Stripe, primarily working on models for loss estimation. Previously, I was also a Data Scientist Intern at Stripe.

From 2017-2022, I completed my PhD in Neuroscience in the Harvey Lab at Harvard Medical School, where I was supported by an NSF Graduate Research Fellowship and an NIH NRSA F31 Predoctoral Fellowship. My main project focused on using two-photon optogenetics and calcium imaging to probe functional microcircuit architecture in mouse visual cortex. I developed new methodological techniques and analyses of large-scale data to understand how neurons causally influence each other and which features of their activity and tuning properties contribute. My dissertation can be read here.

In 2017, I received my undergraduate degree in Bioengineering from Stanford University. I conducted neuroscience research in the Deisseroth Lab on CLARITY, circuit-level mechanisms in memory encoding and retrieval, CRISPR, and multisensory virtual reality systems.

Publications
  1. Jaffe AW. Optical investigation of microcircuit computations in mouse primary visual cortex. (2022). [Doctoral dissertation]. Harvard University. PDF
  2. Kafashan MM, Jaffe AW, Chettih SN, Nogueira R, Arandia-Romero I, Harvey CD, Moreno-Bote R, Drugowitsch J. Scaling of sensory information in large neural populations shows signatures of information-limiting correlations. Nature Communications 12, 473 (2021). [PDF]
  3. Sylwestrak EL, Rajasethupathy P, Wright MA, Jaffe A, Deisseroth K. Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution. Cell 164, 1–13 (2016). [PDF]
  4. Rajasethupathy P, Sankaran S, Marshel JH, Kim CK, Ferenczi E, Lee SY, Berndt A, Ramakrishnan C, Jaffe A, Lo M, Liston C, Deisseroth K. Projections from neocortex mediate top-down control of memory retrieval. Nature 526, 653–9 (2015). [PDF]
Other

In my free time, I enjoy cycling and running, reading, going to museums, finding new food spots, cooking and (occasionally) baking, and attending local music concerts of various genres (funk/metal/classical/you name it). I've most recently played trumpet with the Brookline Symphony Orchestra, and before that, I played in the Dudley Orchestra and Longwood Symphony Orchestra while in Boston. During undergrad, I was in the Stanford Symphony Orchestra.

Check out some of my past performances:

© 2022 Anna Jaffe. All rights reserved.